In a small Brazilian town, there resides an extraordinary duo of identical twins named Elis and Eloá. Their story serves as a beacon of resilience and the remarkable power of the human spirit. Afflicted with Hutchinson-Gilford Progeria Syndrome, a rare and fatal genetic disorder causing accelerated aging, these twins confront their adversities with remarkable grace and strength, earning admiration from people worldwide.
Understanding Hutchinson-Gilford Progeria syndrome
HGPS stands as an exceptionally rare disorder, impacting roughly 1 in 20 million newborns globally. Marked by rapid aging from early childhood, individuals with progeria often display growth delays, diminished body fat and hair, prematurely aged skin, joint stiffness, and severe cardiovascular issues. Typically, those with HGPS have an average life expectancy of about 14.5 years, though some may extend into their late teens or early twenties. This syndrome gained public attention through the film The Curious Case of Benjamin Button.
The condition is caused by a mutation in the LMNA gene, which produces the lamin A protein responsible for maintaining the structural integrity of the cell nucleus. The mutation results in the production of an abnormal version of the protein, called progerin, which causes cells to become unstable and die prematurely.
Elis and Eloá’s journey
Elis and Eloá swiftly captured attention because of their distinctive medical condition. Despite the physical hurdles imposed by progeria, their contagious smiles and steadfast optimism have emerged as beacons of hope and inspiration. Guilherme and Elismar, the twins’ parents, have dedicated their lives to offering the utmost care for their daughters, striving to ensure they experience as normal a life as feasible within the confines of their condition.
The family’s path has been far from easy. Their daily life is filled with demanding medical routines, including physiotherapy, aimed at addressing joint stiffness and preserving mobility. Despite these challenges, Elis and Eloá approach each day with remarkable bravery and an unparalleled enthusiasm for life, which is truly remarkable.
A global community of support
Elis and Eloá’s narrative has touched hearts worldwide, sparking a surge of solidarity from individuals and groups committed to promoting awareness about progeria and backing research endeavors. The Progeria Research Foundation, a pivotal entity in this realm, has played a vital role in propelling research forward and furnishing assistance to families grappling with the condition.
Through social media platforms, the twins’ journey is shared with a broad audience, fostering a sense of community and solidarity. Their family’s updates, documenting both the highs and lows of their daily lives, provide invaluable insights into the realities of living with progeria, while also spreading a message of hope and perseverance.
Advances in research and hope for the future
In recent years, there have been remarkable advancements in comprehending and addressing progeria. A notable milestone occurred in 2020 when the U.S. Food and Drug Administration (FDA) granted approval for the first progeria treatment: lonafarnib. This medication has demonstrated efficacy in prolonging the lives of children with progeria by mitigating the accumulation of progerin in cells, thereby decelerating the disease’s advancement.
Though a cure remains elusive, ongoing research presents promising prospects. Scientists are delving into gene-editing methodologies, like CRISPR, as potential means to rectify the genetic mutation at its root. For families such as Elis and Eloá’s, these breakthroughs offer a ray of hope for the future.
And in our other article, we recounted the remarkable story of a girl born without a nose, affectionately dubbed “Voldemort,” who refuses to let her differences define her.
Zendaya’s Bold Cher-Inspired Look at Rock & Roll Hall of Fame: Is It a Fashion Win or Fail
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Even though some people criticized Zendaya’s Cher-inspired outfit, others praised her for it. Cher was inducted into the Rock & Roll Hall of Fame just months after she expressed disappointment about not being recognized sooner.
At the Rock & Roll Hall of Fame Induction Ceremony in Cleveland, Ohio, on October 19, 2024, Zendaya paid tribute to the music legend Cher by wearing a sparkling dress. The 27-year-old actress and fashion icon spoke warmly about Cher, sharing her admiration for the artist.
Zendaya’s beaded gown featured a design that exposed her midriff, highlighting her fit figure.
Zendaya’s dress at the event featured criss-cross straps across her chest and had cutouts that made the gold and skin-colored gown look both bold and stylish. The design was daring yet chic.
Zendaya’s outfit paid homage to a famous look from the 1970s when Cher was known for her daring fashion choices and her own music and variety show.
Along with her stunning gown, Zendaya styled her long, sleek black hair with a perfect middle part. She wore golden stiletto heels that made her tall figure even more striking.
At one point, she added a luxurious white coat with gold embroidery to her outfit. She kept her accessories simple, adding just a bit of sparkle with her bracelets and ring.
In addition to taking solo photos, Zendaya posed with other stars like Dua Lipa and Cher, who wore an all-black outfit.
As the evening went on, Zendaya honored Cher with a heartfelt speech that resonated with everyone in the audience.
Standing confidently at the podium, Zendaya shared her admiration for Cher and the impact she has had on many generations.
“Thank you, Cher,” Zendaya began. “Thank you for being an advocate, for paving the way for many people to speak their truth and be open-hearted.”
Quoting Cher, Zendaya added, “‘You should never be inhibited by what people expect you to do.’ I hope we can all live by those words.”
While Zendaya’s tribute to Cher captivated the audience, her bold outfit sparked mixed reactions online. Many acknowledged her beauty, but some were not fond of her look.
One person commented, “She’s gorgeous, but this is too revealing.” Another asked, “Does she really need to be almost naked? She looks sad in it.”
Someone compared her outfit to a famous pop culture reference, saying, “Zendaya is beautiful, but the dress looks like a ‘Princess Leia’ costume. It leaves nothing to the imagination.”
Others were concerned about the message her outfit sent. “Beautiful, but why do talented women need to undress for attention?” questioned one comment.
Another person noted a trend among celebrities, saying, “Why do women feel like they have to be almost naked to be relevant? It feels wrong.”
Some people criticized the outfit for lacking creativity, with one commenter stating, “Women dressed like this acting ‘edgy’ is old and boring.”
Yet, amidst the criticism, some fans praised Zendaya. “Zendaya outdid herself! She looks absolutely stunning!” said one admirer.
Another fan embraced the Cher-inspired look, saying, “Total Cher vibes! Gorgeous!”
While Zendaya’s outfit sparked conversation, the main focus of the evening was Cher’s long-awaited induction into the Rock & Roll Hall of Fame.
Cher’s career spans seven decades, making her influence on music, film, and pop culture truly remarkable.
From her early days with Sonny Bono to becoming a solo superstar, Cher has continuously evolved and stayed relevant in the entertainment world.
During her acceptance speech, Cher spoke candidly about the challenges she has faced in her life and career, saying it was easier to get divorced twice than to receive this honor.
Despite the hurdles, Cher emphasized the importance of perseverance, stating, “The one thing that I have never done is give up.”
Her speech included personal stories, from her childhood dreams to her groundbreaking success with the song “Believe,” which changed the music industry.
Cher shared how the song came about almost by accident but became a defining moment for her.
With humility, she said, “I’m a good singer, not a great singer. You know what? I’ll take it.” At one point, she addressed the women in the audience.
Cher expressed admiration for women’s strength, saying, “We’ve been down and out, and we keep going. We are special.”
She concluded her speech by thanking her family and close friends.
Before this honor, Cher had expressed her frustration about not being inducted sooner. In December 2023, she appeared on “The Kelly Clarkson Show” and shared her feelings about the snub.
During the interview, Kelly praised Cher’s career, saying, “You have number ones spanning seven decades!” Cher replied, “Two of us have.”
When Kelly learned that Cher wasn’t in the Hall of Fame at that time, she was shocked. Cher responded sharply, “I wouldn’t be in it now if they gave me $1 million.”
However, when the time came for Cher to be inducted, she accepted the honor with gratitude and defiance.
In May 2024, ahead of the induction, Cher attended the premiere of “Bob Mackie: Naked Illusion,” where she expressed appreciation for those who supported her induction.
While talking to Entertainment Tonight, Cher thanked David Geffen and John Sykes for their efforts.
Yet, true to her style, she hinted that she would speak her mind at the ceremony. “I’m going to have some words to say. I’m going to accept it as me,” she added. Cher certainly did not hold back during her induction acceptance speech.
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